Research progress of the interaction between gut microbes and brain gut axis
TIAN Zu-hong
NIE Yong-zhan
Abstract：Intestinal microbes play a key role in the regulation of brain gut axis, and have an important influence on the stress response, anxiety, depression and cognitive function of the host. Intestinal flora imbalance may lead to multiple central nervous system diseases, including multiple sclerosis, Parkinson's disease, autism, etc. In this review, the anthors collect past ten-year researches of intestinal microbial involved in central nervous system diseases, make an in-depth analysis of the two-way regulation mechanism of microbiome-gut-brain axis, summarize restricting factors and regulation strategies of micro ecological stability, and provide a new idea for the application of micro ecological therapy in clinical diagnosis and treatment of nervous system diseases.
Keywords：gut microbiotamicrobiome-gut-brain axisdisease
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 302-307 )