The Cutting Edge of Research Advance on the relationship between intestinal microecology and hepatocellular carcinoma
JIANG Jian-wen
REN Zhi-gang
ZHENG Shu-sen
Abstract：Due to the close anatomical and functional relationship between the liver and the intestine, intestinal microflora, interact with liver function through the liver-intestinal axis. It plays an important role in the development of the liver inflammation, fibrosis and tumor. Intestinal microflora disorders promote the progress of hepatocellular carcinoma (HCC), which is an international breakthrough in the pathogenesis of HCC in experimental animals. Key feature strains of the intestinal microflora may become new biomarkers and therapeutic targets of HCC. With the development of the second generation high throughput sequencing technology, the research of metagenomics has opened up a new way for us to understand the relationship between intestinal microflora and HCC from the great depth and breadth.
Keywords：intestinal microecologyhepatocellular carcinomametagenomicsinflammation-carcinoma shiftholistic integrative hepato-enterology
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 264-266,283 )