Research progress of systemic chemotherapy for primary hepatocellular carcinoma
WANG Hui
ZHANG Tao
LI Wen-gang
DUAN Xue-zhang
Abstract:Primary hepatocellular carcinoma is a malignant tumor with high incidence in China, characterized by insidious onset, rapid progress, and more difficulties in early diagnosis. Most of the patients were diagnosed with advanced stage, but only a few cases can be operated and the survival time of the patients treated with supportive treatment is shorter than that of the patients. For the middle and advanced stage of hepatocellular carcinoma, systemic treatment is often used as a main means of palliative treatment, to prolong the survival period and improve life quality of paetients. In the past, some traditional cytotoxic drugs have been on trial, which is showed with lower effective rate and a lack of high-level evidence-based medicine evidence to support its survival benefit. In recent years, many clinical studies on the chemotherapy for primary hepatocellular carcinoma have been carried out and published, many of these results are encouraging. This paper comprehensively reviewed the research achievements on chemotherapy.
Keywords:carcinomahepatocellularchemoembolizationtherapeuticliver neoplasmsanti-neoplastic agents
Publication Date:2016-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:8( 241-248 )
