Current status and challenges of immunotherapy in hepatocellular carcinoma
QU Jian-hui
ZHANG Cui-hong
LI Ruo-ran
LU Yin-ying
Abstract：Tumor immunotherapy is a promising, novel treatment strategy that may lead to improvements in both treatment-associated toxicity and outcome. The key point for tumor immunotherapy is to inhibit immune checkpoint,overcome tumor immune escape and reconstruct anti-tumor immune mechanism. For hepatocellular carcinoma (HCC), immunotherapy is still in an early stage of development. Immunotherapy, alone or in combination with other therapy methods, might provide an effective control of tumor cell growth. However, the overall therapeutic efficacy is still limited. Here, this review summarized current status and challenges of immunotherapy in hepatocellular carcinoma by combination of its progress of research and application.
Keywords：carcinomahepatocellularimmune systemimmunotherapy
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 193-197,208 )