Research progress of antiviral treatment for interruption of mother-to-child transmission of HBV during pregnancy
WEI Hong
PANG Qiu-mei
Abstract：HBV infection is a worldwide health problem, and mother-to-child transmission is the main source of chronic HBV infection. Chronic vertical transmission may occur in 5%-15% of infants born to HBeAg-positive mothers even after immunoprophylaxis. Previous studies indicate that antiviral therapy with nucleos(t)ide analogues is safe and efficient, which may improve the interruption of vertical transmission and reduce the effect of HBV infection on pregnancy and delivery outcome. This review focuses on indications of antiviral therapy, drug choosing, time of initiating and ending of antiviral agents, medication monitoring, postpartum breast-feeding and newborn follow-up, in order to provide efficient methods for reducing mother-to-child transmission of HBV.
Keywords：hepatitis B virusantiviral agentsmaternal-fetal exchange
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 73-76 )