Clinical characteristics of 21 deaths with severe fever with thrombocytopenia syndrome
XU Xiao-wen
JIANG Mei
LIU Jing-yu
LIU Tao
MU Xiao-dong
LIU Jun
Abstract：Objective To summarize the clinical characteristics of deaths with severe fever with thrombocytopenia syndrome (SFTS). Method The clinical data and laboratory findings of 21 deaths with SFTS were analyzed retrospectively. Results Totally 71.4% of the patients had underlying diseases. The average interval from onset to death was 9 days. The main clinical symptoms were fever (100%), anorexia (90.5%), fatigue and muscle soreness (85.7%), nausea and vomiting (61.9%), headache and dizziness (42.9%), etc. Neurological symptoms were found in 90.5% of the patients, pulmonary infection in 52.4% of the patients and hemorrhagic manifestations in 47.6% of the patients. PLT and WBC decreased in 100% and 81.0% of the patients, respectively. Proteinuria was found in 79.2% of the patients. ALT and AST elevated in 81.0% and 90.5% of the patients, respectively. The main cause of deaths were respiratory and circulatory failures. Conclusions SFTS develops quickly in patients with death as their outcome, and multiple organ dysfunctions may occur on admission in those patients, which should be paid due attention to in the diagnosis and treatment of SFTS patients.
Keywords：thrombocytopeniafeverBunyaviridae infectionsphleboviruspatients
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 41-43 )