Clinical characteristics of brucellosis in pediatric patients in Xinjiang Uyghur Autonomous Region

WANG Yan; GAO Yan-xin; SUN Xiao-feng

doi:10.3969/j.issn.1007-8134.2016.01.006

Abstract：Objective To investigate the prevalence, clinical characteristics, and treatment of brucellosis in pediatric patients in Xinjiang Uyghur Autonomous Region(Xinjiang).Methods Clinical characteristics and therapy of brucellosis in 16 pediatric patients were analyzed retrospectively.Results All the 16 patients were no more than 15 years old, and most of them lived in the agricultural and pastoral areas. the main clinical manifestations were fever, joint pain and hepatosplenomegaly and lymph node enlargement. The combination of doxycycline and rifampin was used in the patients more than 12 years old, and the combination of rifampin and sulfamethoxazole in patients less than 12 years old. Among 16 patients, 15 were cured, and 1 patient combined with leukemia had poor efficacy.Conclusions Clinicians should have a detailed understanding of the epidemiological data of the patients, who get recurrent fevers of unknown reason, and Brucella agglutination test should be made timely.Brucella antibody test can be used as a routine examination in children with unknown fever. Early diagnosis and timely treatment facilitate the recovery of children in the acute phase.