Serological survey of past infection with a novel reovirus in different populations
HU Yan
MAO Da
LIU Ze
JIANG Qi-yu
XIE Guo-ming
BAI Bing-ke
Abstract：Objective To evaluate the prevalence of past infection with a novel reovirus in different populations. Methods The serum samples were taken from 97 healthy people and 219 patients with hand, foot and mouth disease (HFMD), diarrhea, measles and hepatitis B treated in our hospital. The prevalence of the novel reovirus-specific IgG antibody in sera was detected by using a neutraliza-tion assay. Results The neutralization assay demonstrated that the positive rates of the novel reovirus-specific IgG antibody were 29.90%in healthy controls, 70.83%in HFMD group, 90.22%in hepatitis B group, 90.70%in measles group and 100%in diarrhea group, and the median IgG antibody titers were 1∶32, 1∶64, 1∶128, 1∶128 and 1∶256 in those groups respectively. Conclusions The positive rates and titers of a novel reovirus-specific IgG antibody are significantly different between the healthy population and patients with different diseases.
Keywords：reoviridae infectionsserotypingneutralization tests
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 207-209 )