Clinical analysis of 117 patients with brucellosis in Xinjiang Uyghur Autonomous Region

WANG Yan; SUN Xiao-feng; XIANG Yang; ZHANG Yue-xin

Abstract：Objective To investigate the prevalence, clinical characteristics, laboratory findings and treatment outcome of bru-cellosis in Xinjiang Uyghur Autonomous Region (Xinjiang). Methods Clinical characteristics and therapeutic efficacy were analyzed in 117 patients with brucellosis admitted to our hospital from Jul. 2012 to Apr. 2014. Results The incidence of brucellosis was higher from April to September in Xinjiang and brucellosis mainly occurred in livestock-related personnel. The main clinical manifestations were fever, sweating, fatigue and joint pain, and hepatosplenomegaly and lymph node enlargement were found in some patients. ALT, AST and GGT increased in some patients. The combination of doxycycline and rifampin achieved a high improvement rate (97.44%). Conclusions Brucellosis is a more frequent infectious disease in Xinjiang, so local authorities should strengthen public education on brucellosis prevention and management, and clinicians should pay much attention to the clinical characteristics of brucellosis and its complications and comorbidities, and give standard antimicrobial therapy.