Clinical analysis of 53 patients with severe fever with thrombocytopenia syndrome in People ’s Hospital of Penglai city

CONG Li-xian

Abstract：Objective To investigate the prevalence and clinical features of severe fever with thrombocytopenia syndrome (SFTS) so as to improve the understanding of the disease. Methods Clinical data of 53 patients with SFTS treated in the People's Hos-pital of Penglai from 2011 to 2013 were analyzed retrospectively. Results SFTS was highly distributed with peak incidence from June to September. Peasants accounted for the largest proportion (94.34%), and spatial aggregation was found in 14 patients. All patients had fever, the main symptoms included fatigue, body pain, anorexia and nausea, and the main signs included inguinal lymph node enlargement and tenderness (64.15%), and the tongue and limbs tremor (58.49%). Laboratory examination results showed that at the early stage of the onset, WBC (94.34%), PLT (88.68%) and eosinophilic granulocyte ratio (98.11%) decreased, ALT, AST, LDH, CK-MB and fasting blood glucose elevated, and proteinuria occurred. Thirty-nine patients were cured, and 14 (26.42%) died. Patients with older age, presence of underlying diseases, failure to receive timely diagnosis and treatment after onset, and presence of respiratory symptoms have more severer condition, and higher mortality. Conclusions Early detection, early diagnosis and early treatment, prevention and treatment of complications, and strengthening the disinfection, isolation and protection measures, can help reduce the case fatality rate.