Clinical characteristics in 422 patients with severe fever with thrombocytopenia syndrome
XU Zhe
CUI Ning
CHEN Wei-wei
QIN En-qiang
NIE Wei-ming
YUAN Chun
TU Bo
XU Wen
ZHAO Min
Abstract：Objective To investigate the epidemiological and clinical features in patients with severe fever with thrombocytope-nia syndrome (SFTS). Methods A retrospective study was conducted in 422 SFTS patients with detailed medical records including epi-demiology, clinical manifestations, laboratory findings, treatment procedures and prognosis, who were treated in a certain hospital in Xinyang City, Henan Province, from Apr. 2007 to May 2011. Results Adult farmers accounted for a large proportion, and the onset of the disease mainly occurred from May to July each year. A history of tick bites was found in 21.80%of the patients. The major clinical symptoms were fever, fatigue, muscle pain, loss of appetite, general malaise, diarrhea, nausea, vomiting and headache. The major clini-cal sign was enlargement and tenderness of superficial lymph node. Laboratory findings were characterized by decrease in WBC and PLT, and elevated levels of ALT, AST, CK and LDH. Sixty-eight patients died, with the fatality rate of 16 . 11%. Conclusions The clinical manifestations of the patients with SFTS may be diverse, usually accompanied by obvious abnormality of biochemical markers. Supportive treatment should be initiated in clinical practice.
Keywords：thrombocytopeniafeverBunyaviridae infectionsphleboviruspatients
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 28-32 )