Screening value of AIDS patients complicated with penicilliosis marneffei when AST elevates more than twice the upper limit of normal and higher than ALT
XIE Zhi-man
Abstract：Objective To evaluate the screening value of AIDS patients complicated with penicilliosis marneffei when AST elevates more than twice the upper limit of normal and higher than ALT. Methods A total of 1045 AIDS patients complicated with suspected penicilliosis marneffei (PSM) in Guangxi undertook the examinations by“gold standard”(Penicillium marneffei found in culture of blood, marrow and tissue, or by biopsy) and the preliminary diagnostic standard. The diagnostic value of the preliminary diagnostic standard in AIDS patients complicated with PSM was evaluated. Results The sensitivity of the preliminary diagnostic standard was 45.79%, false negative rate 42.11%, specificity 90.64%, false positive rate 9.36%, accuracy rate 82.49%, positive likelihood ratio 4.89, negative likelihood ratio 0.60, positive predictive value 52.10%, and negative predictive value 88.27%.Conclusions When AST level elevates more than twice the upper limit of normal and higher than ALT level, AIDS patients can not be diagnosed as PSM, but great concern should be given to the occurrence of PSM.
Keywords：mycosesacquired immunodeficiency syndromePenicilliumaspartate aminotransferases
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 305-307 )