The application of the matrix-assisted laser desorption ionization time of flight mass spectrometry in the infectious disease pathogens and drug resistance detection
MAO Yuan-li
QIN Jian-cheng
LI Bo
Abstract：Matrix-assisted laser desorption ionization time of flight mass spectrometry(MALDI-TOF-MS)works as a method for proteomics analysis with characteristics of high throughput, high sensitivity, simple operation, quick results and the self-built da-tabase. This technology has been applied in infectious disease pathogen identification and detection of drug resistance, and is of great significance to timely diagnosis and treatment. By introducing the research status of the technology in its quick identification and drug resistance detection of pathogenic microorganisms of such specimens as strains and sterile, this paper discusses its chal-lenges and application prospects.
Keywords：spectrometrymassmatrix-assisted laser desorption ionizationbacteriological techniquescommunicable diseases
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 270-273,278 )