Research progress of HIV/HBV co-infection
MAO Lin
LI Wu
WANG Xi-cheng
Abstract：The same routes of transmission of HIV and HBV increase the risk of HIV/HBV co-infection. Both kinds of the viruses interact by promoting each other's gene transcription and replication, so genetic recombination among them may produce ad-ditional mutations and affect the treatment effect. Some nucleos (t)ide analogues such as lamivudine, emtricitabine, entecavir and tenofovir, have both anti-HIV and anti-HBV activities, and it is likely to induce the emergence of resistant strains of HIV and/or HBV and cross resistance of the antiviral agents if they are not properly used, which may lead to serious effects on the prognosis of AIDS and chronic hepatitis B. This article reviews the research progress of HIV/HBV co-infection.
Keywords：HIVhepatitis B virusepidemiologyantiviral agents
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 126-128 )