Therapeutic efficacy of polyene phosphatidylcholine on hepatic injury in patients with primary liver cancer receiving transcatheter arterial chemoembolization
HE Dong-lin
WU Xiao-xiong
LUO Ming
Abstract：Objective To investigate the therapeutic efficacy of polyene phosphatidylcholine on hepatic injury in patients with primary liver cancer (PLC) receiving transcatheter arterial chemoembolization (TACE). Methods A total of 66 PLC patients were randomized into a treatment group and a control group, with 33 patients in each group. Both the groups received TACE. Since two days before TACE, the control group began to receive routine liver-protecting therapy with drugs such as glutathione, while the treatment group received intravenous administration of polyene phosphatidylcholine, 930 mg daily, in addition to the routine liver-protecting therapy. The levels of TBIL, PA, ALT and AST were detected before drug therapy and on the 3rd day after giving TACE. Results As compared with the control group, TBIL, ALT and AST in the patients of the treatment group, who had received polyene phosphatidylcholine, significantly improved (P<0.05). Conclusion Treatment with polyene phosphatidylcholine has good effect on hepatic injury in PLC patients receiving TACE.
Keywords：carcinomahepatocellularliver diseaseschemoembolizationtherapeuticphosphatidylcholines
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 102-104 )