Cost-effect analysis of the immunization strategy of infant hepatitis B vaccination implemented in Tianjin from 1992 to 2010
HE Hai-yan
ZHAO Ying
CHEN Jing
WU Wei-shen
Li Chao
SHAN Ai-lan
Abstract：Objective To investigate the effectiveness and economic benefits of the immunization strategy of infant hepatitis B vaccination implemented in Tianjin from 1992 to 2010. Methods The related data were collected from hepatitis B vaccine im-munization reports and serological surveillance results from Tianjin Center for Disease Control and Prevention, and from a large-scale community surveillance of hepatitis B and HBV-related diseases. Patients with hepatitis B and HBV-related diseases were the subjects of economic burden investigation. Cost-benefit analysis method was used to make a comprehensive evaluation of the immu-nization strategy. Results Under the present immunization strategy, the reported morbidity of the population aged younger than 20 in Tianjin decreased by 33.00%from 14.14/100 000 in 1992 to 9.46/100 000 in 2010. The number of patients with HBsAg positives decreased by 98 984 cases, the number of patients with chronic hepatitis B decreased by 17 830 cases, the number of patients with HBV-related liver cirrhosis decreased by 5310 cases, and the number of patients with liver cancer decreased by 1606 cases. The total benefit was 47.351 billion yuan, and the net benefit was 47.312 billion yuan with a benefit/cost ratio of 1213∶1. Conclusion The current immunization strategy of infant hepatitis B vaccination implemented in Tianjin acquires huge economic and social benefits.
Keywords：hepatitis Bchronichepatitis B vaccinesimmunizationsecondary
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 89-92 )