Therapeutic effect of transcatheter arterial chemoembolization on spontaneous rupture and hemorrhage in patients with decompensated cirrhosis complicated by advanced primary liver cancer
SU Shu-hui
CHANG Xiu-juan
WEI Zhao-yong
LU Yin-ying
WANG Chun-ping
YANG Yong-ping
Abstract：Objective To assess the therapeutic effect of transcatheter arterial chemoembolization (TACE) and medical treat-ment on spontaneous rupture and hemorrhage of hepatocellular carcinoma in patients with decompensated cirrhosis complicated by advanced primary liver cancer. Methods Clinical data of 147 decompensated cirrhotic patients with spontaneous rupture and hem-orrhage of primary hepatocellular carcinoma were analyzed retrospectively. Among the 147 patients, 92 received medical treatment (medical treatment group) and 55 received TACE in addition to medical treatment (TACE+medical treatment group). The effect on stopping bleeding during 24 hours and the causes of death were compared between the two groups. Results The rates of stopping bleeding during 24 hours were 83.6% and 64.1%, respectively, in TACE+medical treatment group and medical treatment group (P<0.05). The differences in the causes of death and median survival were not significant between the two groups. Conclusions Although short-term effect of TACE on stopping bleeding is superior to that of medical treatment in patients with decompensated cirrhosis com-plicated by advanced primary liver cancer suffering from spontaneous rupture and hemorrhage of hepatocellular carcinoma, TACE shows no improvement in prolonging survival in those patients.
Keywords：liver neoplasmschemoembolizationtherapeuticliver cirrhosisrupturehemorrhagetreatment outcome
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 86-88,92 )