Comparison of the laboratory indicators detected for the first time after admission between the patients with ordinary and severe hand, foot and mouth disease
YANG Jun-lian
ZHOU Zhi-ping
XU Wen
TANG Bo
YANG Xin-xin
ZHAO Min
CHEN Wei-wei
Abstract:Objective To analyze the laboratory indicators detected for the first time after admission between the patients with ordinary and severe hand, foot and mouth disease (HFMD), and provide laboratory evidence for early identification of severe HFMD patients. Methods Forty-seven ordinary HFMD patients and 36 severe HFMD patients (1-4 years old) were enrolled in the study. The laboratory indicators detected for the first time after admission were collected and analyzed by SPSS statistical software. Results The severe HFMD children were 1-2 years old, and the majority of them were infected by human enterovirus 71. The pro-portions of severe HFMD children with abnormal white blood cell count and neutrophil percentage, and PLT level of severe HFMD children were significantly higher than those of ordinary HFMD children. The level of low density lipoprotein cholesterols (LDL-C) and its abnormality in severe HFMD children were significantly higher than those in ordinary HFMD children. Conclusions The laboratory indicators detected for the first time after admission is of great importance in early identification of severe HFMD patients. This study identifies the role of abnormally elevated level of PLT and LDL-C in suggesting the occurrence of severe HFMD.
Keywords:handfoot and mouth diseaseenteroviruscritical illnesslaboratories
Publication Date:2014-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:4( 31-34 )
