Research progress in relationship between IL-1β and psoriasis
LIU Hongjie
LIU Junlin
Abstract：Psoriasis is a chronic inflammatory skin disease,and its pathogenesis is not yet fully clear.At present,researches suggest that immune abnormalities play a significant role in the occurrence and development of psoriasis.Interleukin-1β(IL-1β)is an important member of the interleukin-1 family and has a strong pro-inflammatory effect.In psoriasis lesions,the expression of IL-1β is significantly increased and plays a key role in the pathophysiological process.In addition,the polymorphism of the genes of IL-1β can affect its transcription and expression,and is closely related to psoriasis.In this paper,the research progress in relationship between IL-1β and psoriasis is reviewed.
Keywords：Interleukin-1β(IL-1β)GenePolymorphismPsoriasis
Publication Date：2025-05-30
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 576-579 )