A Case Analysis of Idiopathic Multicentric Castleman Disease-TAFRO Syndrome with Thrombotic Microangiopathy-Induced Renal Injury
Abstract：Idiopathic multicentric Castleman disease (iMCD) is a rare and life-threatening disease characterized by systemic inflammatory symptoms, polyclonal lymphocyte proliferation, cytopenia, and multi-organ dysfunction [1]. TAFRO syndrome (Thrombocytopenia, Anasarca, Myelofibrosis, Renal Dysfunction, and Organomegaly, TAFRO) is a group of clinical manifestations characterized by thrombocytopenia (T), generalized edema (A), fever (F), myelofibrosis or renal dysfunction (R), and organomegaly (O), with normal immunoglobulin levels [2].
Keywords：Castleman diseaseTAFRO syndromerenal thrombotic microangiopathy
Publication Date：2025-03-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 260-264 )