Application of Blood Lactate in Critical Care: Expert Consensus in Emergency Medicine
Abstract：In the 1920s, Swedish and British scientists revealed the role of lactate in anaerobic metabolism in muscles [1], discovering that lactate is a metabolic product of hypoxic tissues, and its serum level can reflect tissue oxygenation status and metabolic state [2]. In the mid-20th century, arterial blood lactate monitoring was widely used in clinical practice. An increase in lactate levels is usually associated with inadequate tissue perfusion, hypoxemia, and metabolic disorders, especially in patients with critical conditions such as shock, sepsis, and multiple organ failure, where it is considered an important prognostic indicator.
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Publication Date：2025-10-10
Online Publishing Date：2025-11-07(First online date of this platform, not the publication date of the document)
Pages：10( 829-838 )