Clinical Effect of Wuxian Qizhen Therapy Combined with Exercise Therapy on Patients with Limb Dysfunction After Stroke

doi:10.16458/j.cnki.1007-0893.2025.16.012

Abstract：Objective: To investigate the clinical effect of Wuxian Qizhen therapy combined with exercise therapy in patients with limb dysfunction after stroke. Methods: A total of 92 patients with post-stroke limb dysfunction who were treated at Yongmei Group General Hospital from February 2020 to February 2024 were selected as the study subjects and divided into control group and observation group according to treatment methods, with 46 cases in each group. The control group received exercise therapy, while the observation group received Wuxian Qizhen therapy combined with exercise therapy. The treatment effects, limb function before and after treatment, serum neurotrophic factor levels, and coagulation function were compared between the two groups. Results: The treatment effect of the observation group was better than that of the control group, with a statistically significant difference (Z = -2.073, P < 0.05). After treatment, the Fugl-Meyer Assessment (FMA) and Modified Barthel Index (MBI) scores of the observation group were higher than those of the control group, with statistically significant differences (P < 0.05). After treatment, the serum levels of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) in the observation group were higher than those in the control group, with statistically significant differences (P < 0.05). After treatment, the D-dimer (D-D) and fibrinogen (Fib) levels in the observation group were lower than those in the control group, and the prothrombin time (TT) was longer in the observation group, with statistically significant differences (P < 0.05). Conclusion: Wuxian Qizhen therapy combined with exercise therapy has a significant clinical effect in patients with limb dysfunction after stroke, which helps improve the level of neurotrophic factors and correct the hypercoagulable state of the body.