The role of ETS1/NF-κB signaling pathway-mediated communication between mesangial cells and podocytes in diabetic kidney disease and the intervention of traditional Chinese medicine
Abstract：According to the International Diabetes Federation, there were approximately 463 million diabetic patients globally in 2019, and it is expected to increase to 700 million by 2045, among whom 30% to 40% progress to diabetic kidney disease (DKD). The pathogenesis of DKD is very complex, and its treatment is much more difficult than that of general kidney diseases, with a poor prognosis. ETS1 is mainly expressed in glomerular mesangial cells (MCs) and can induce proliferation of MCs and extracellular matrix expression under high glucose conditions, participating in the progression of DKD.
Keywords：Diabetic Kidney DiseaseE26 Transcription Factor 1Nuclear Factor Kappa BCommunicationTraditional Chinese Medicine
Publication Date：2025-05-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 454-456,封3 )